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Saframycin A
CAS No. 66082-27-7
Saframycin A( NSC 325663 )
Catalog No. M15514 CAS No. 66082-27-7
A heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSaframycin A
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NoteResearch use only, not for human use.
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Brief DescriptionA heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro.
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DescriptionA heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro; shows potent antiproliferative effects in leukemia- and tumor-derived cells; induces nuclear translocation of GAPDH in cancer cells.
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In Vitro——
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In Vivo——
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SynonymsNSC 325663
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number66082-27-7
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Formula Weight562.579
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Molecular FormulaC29H30N4O8
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=C(C(C2=C(C1=O)[C@@H](N3[C@H]([C@H]4N([C@@H]([C@@H]3C#N)CC5=C4C(C(OC)=C(C5=O)C)=O)C)C2)CNC(C(C)=O)=O)=O)C
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Chemical NameN-[[(6S,7R,9R,14aS,15R)-7-Cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxopropanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xing C, et al. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5862-6.
2. Ishiguro K, et al. Biochemistry. 1978 Jun 27;17(13):2545-50.
3. Spencer JR, et al. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4884-8.
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